Going to your hotels/guesthouses from Hong Kong International Airport is not a hassle even with big luggages around. For budget travelers like us, taxi is not an option so we always take the airport bus, A21.
If you’re hotel is in Tsim Sha Tsui, this is the bus you’re going to take. Fare is 33 HKD, accepts Octopus Cards or prepare exact fare. It has spacious luggage compartments located near the door so that you can sit comfortably while travelling and enjoy the view of Tsing Ma bridge. Travel time from the airport to Taisan guesthouse is 45 minutes, bus stop number 13 from the airport.
If you want a faster way to get to the city from the airport, take the Airport Express train.